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    • ankylosing spondylitis is a chronic progressive disease that manifests itself as inflammation of the joints of the spine.
    • with ankylosing spondylitis: The daily dose should be 60 mg. With the insufficient weakening of the symptoms, the rate can be increased up to 90 mg to obtain the maximum drug effect. At the achievement of clinical stabilization of the patient, it is required to reduce to 60 mg 1 time per day.

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